Gonadotropins: Stimulate ovulation in women with low hormone levels.
Brief information about it:
Gonadotropins are a group of hormones that stimulate the ovaries to produce eggs. They are often used in women with low hormone levels or infertility to induce ovulation.
Uses:
· Infertility: Gonadotropins are used to stimulate ovulation in women with infertility due to low hormone levels.
· In vitro fertilization (IVF): They are also used in conjunction with IVF to help multiple eggs develop for retrieval.
Mechanism of action:
Gonadotropins mimic the natural hormones produced by the pituitary gland, which stimulate the ovaries to produce eggs. The specific type of gonadotropin used depends on the individual’s needs.
Elimination half life:
The elimination half-life of gonadotropins varies depending on the specific type and formulation. However, it generally ranges from a few hours to a few days.
Route of Administration:
Gonadotropins are typically administered through injections. They can be self-injected at home or administered by a healthcare professional
Side effects:
Gonadotropin therapy may cause some side effects, including:
- Ovarian hyperstimulation syndrome (OHSS): This is a serious condition that can occur when the ovaries become overstimulated. Symptoms include abdominal pain, bloating, and weight gain.
- Multiple pregnancy: Gonadotropin therapy can increase the risk of multiple pregnancies.
- Flu-like symptoms
- Mood swings
- Headaches
- Injection site reactions
Dose:
The appropriate dose of gonadotropins will depend on your individual needs and medical history. Your healthcare provider will monitor your hormone levels and adjust the dosage as needed.
Precautions:
Before starting gonadotropin therapy, it’s important to discuss any potential risks with your healthcare provider. Some precautions include:
- History of ovarian hyperstimulation syndrome (OHSS): If you have a history of OHSS, you may be at increased risk.
- Multiple pregnancies: Gonadotropin therapy can increase the risk of multiple pregnancies.
- Pregnancy: Gonadotropins should not be used during pregnancy.
