Phentermine-topiramate: Helps with weight loss by reducing appetite.

Brief information about it:
Phentermine-topiramate is a combination medication used to help people with obesity or overweight lose weight and keep it off. It works by reducing appetite and making you feel full sooner.
Uses:
· Weight loss: Phentermine-topiramate is used in conjunction with a reduced-calorie diet and increased physical activity to help people lose weight.
· Maintaining weight loss: It may also be used to help people maintain weight loss after they’ve lost a significant amount of weight.
Mechanism of action:
Phentermine-topiramate works in two ways:
- Phentermine: Increases the release of norepinephrine, a chemical that affects appetite and mood.
- Topiramate: Reduces the activity of certain nerve cells in the brain that are involved in appetite and weight control.
Elimination half life:
The elimination half-life of phentermine-topiramate is approximately 13 hours. This means that it takes about 13 hours for half of the medication to be eliminated from your body.
Route of Administration:
Phentermine-topiramate is available in extended-release capsules. It is taken by mouth once a day, usually in the morning.
Side effects:
- Dry mouth
- Constipation
- Dizziness
- Insomnia
- Taste changes
- Heart rate changes
- Increased blood pressure
Serious side effects can also occur, such as:
- Allergic reactions
- Suicidal thoughts
- Heart problems
- Seizures
Dose:
The appropriate dose of phentermine-topiramate will depend on your individual needs and medical history. Your healthcare provider will determine the best dose for you.
Precautions:
Before taking phentermine-topiramate, it’s important to discuss any potential risks with your healthcare provider. Some precautions include:
- Heart problems: If you have a history of heart problems, you may be at increased risk.
- Glaucoma: Phentermine-topiramate may worsen glaucoma.
- Pregnancy and breastfeeding: Phentermine-topiramate should not be used during pregnancy or breastfeeding.
- Substance abuse: If you have a history of substance abuse, you may be at increased risk.